OPC configuration for SCADA as client or server won't have much problem as IntegraXor will automatically configure the registry entries for DCOM. However, the remote OPC client/server may be tricky if the remote OPC client/server itself doesn't automatically configure the necessary entry.
Automatic configuration of the remote client/server for granting external access can be done by executing registry file, which can be requested or download from IntegraXor website. Alternatively, it can be created manually by copying the following code to paste into a new text file, then save as remote-opc.reg.
Windows Registry Editor Version 5.00 [HKEY_CLASSES_ROOT\AppID\{13486D44-4821-11D2-A494-3CB306C10000}] @="OpcEnum" "AuthenticationLevel"=dword:00000001 "ServiceParameters"="-Service" "AccessPermission"=hex:01,00,04,80,9c,00,00,00,b8,00,00,00,00,00,00,00,14,00,\ 00,00,02,00,88,00,06,00,00,00,00,00,14,00,07,00,00,00,01,01,00,00,00,00,00,\ 05,0a,00,00,00,00,00,14,00,1f,00,00,00,01,01,00,00,00,00,00,05,07,00,00,00,\ 00,00,14,00,1f,00,00,00,01,01,00,00,00,00,00,01,00,00,00,00,00,00,14,00,1f,\ 00,00,00,01,01,00,00,00,00,00,05,04,00,00,00,00,00,14,00,1f,00,00,00,01,01,\ 00,00,00,00,00,05,02,00,00,00,00,00,14,00,1f,00,00,00,01,01,00,00,00,00,00,\ 05,12,00,00,00,53,00,39,00,30,00,43,00,01,05,00,00,00,00,00,05,15,00,00,00,\ 6b,d6,62,04,07,e9,94,2d,15,25,af,47,eb,03,00,00,01,05,00,00,00,00,00,05,15,\ 00,00,00,6b,d6,62,04,07,e9,94,2d,15,25,af,47,eb,03,00,00 "LaunchPermission"=hex:01,00,04,80,a0,00,00,00,bc,00,00,00,00,00,00,00,14,00,\ 00,00,02,00,8c,00,06,00,00,00,00,00,18,00,1f,00,00,00,01,02,00,00,00,00,00,\ 05,20,00,00,00,20,02,00,00,00,00,14,00,1f,00,00,00,01,01,00,00,00,00,00,05,\ 07,00,00,00,00,00,14,00,1f,00,00,00,01,01,00,00,00,00,00,01,00,00,00,00,00,\ 00,14,00,1f,00,00,00,01,01,00,00,00,00,00,05,04,00,00,00,00,00,14,00,1f,00,\ 00,00,01,01,00,00,00,00,00,05,02,00,00,00,00,00,14,00,1f,00,00,00,01,01,00,\ 00,00,00,00,05,12,00,00,00,69,00,6e,00,64,00,69,00,01,05,00,00,00,00,00,05,\ 15,00,00,00,6b,d6,62,04,07,e9,94,2d,15,25,af,47,eb,03,00,00,01,05,00,00,00,\ 00,00,05,15,00,00,00,6b,d6,62,04,07,e9,94,2d,15,25,af,47,eb,03,00,00 "LocalService"="OpcEnum" [HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\Ole] "DefaultLaunchPermission"=hex:01,00,04,80,dc,00,00,00,ec,00,00,00,00,00,00,00,\ 14,00,00,00,02,00,c8,00,08,00,00,00,00,00,18,00,1f,00,00,00,01,02,00,00,00,\ 00,00,05,20,00,00,00,20,02,00,00,00,00,24,00,1f,00,00,00,01,05,00,00,00,00,\ 00,05,15,00,00,00,6b,d6,62,04,07,e9,94,2d,15,25,af,47,f5,01,00,00,00,00,18,\ 00,1f,00,00,00,01,02,00,00,00,00,00,05,20,00,00,00,22,02,00,00,00,00,14,00,\ 1f,00,00,00,01,01,00,00,00,00,00,05,07,00,00,00,00,00,14,00,1f,00,00,00,01,\ 01,00,00,00,00,00,01,00,00,00,00,00,00,14,00,1f,00,00,00,01,01,00,00,00,00,\ 00,05,04,00,00,00,00,00,14,00,1f,00,00,00,01,01,00,00,00,00,00,05,02,00,00,\ 00,00,00,14,00,1f,00,00,00,01,01,00,00,00,00,00,05,12,00,00,00,73,00,79,00,\ 73,00,74,00,01,02,00,00,00,00,00,05,20,00,00,00,20,02,00,00,01,02,00,00,00,\ 00,00,05,20,00,00,00,20,02,00,00 "MachineLaunchRestriction"=hex:01,00,04,80,dc,00,00,00,ec,00,00,00,00,00,00,00,\ 14,00,00,00,02,00,c8,00,08,00,00,00,00,00,18,00,1f,00,00,00,01,02,00,00,00,\ 00,00,05,20,00,00,00,20,02,00,00,00,00,24,00,1f,00,00,00,01,05,00,00,00,00,\ 00,05,15,00,00,00,6b,d6,62,04,07,e9,94,2d,15,25,af,47,f5,01,00,00,00,00,18,\ 00,1f,00,00,00,01,02,00,00,00,00,00,05,20,00,00,00,22,02,00,00,00,00,14,00,\ 1f,00,00,00,01,01,00,00,00,00,00,05,07,00,00,00,00,00,14,00,1f,00,00,00,01,\ 01,00,00,00,00,00,01,00,00,00,00,00,00,14,00,1f,00,00,00,01,01,00,00,00,00,\ 00,05,04,00,00,00,00,00,14,00,1f,00,00,00,01,01,00,00,00,00,00,05,02,00,00,\ 00,00,00,14,00,1f,00,00,00,01,01,00,00,00,00,00,05,12,00,00,00,73,00,79,00,\ 73,00,74,00,01,02,00,00,00,00,00,05,20,00,00,00,20,02,00,00,01,02,00,00,00,\ 00,00,05,20,00,00,00,20,02,00,00 "MachineAccessRestriction"=hex:01,00,04,80,c4,00,00,00,d4,00,00,00,00,00,00,00,\ 14,00,00,00,02,00,b0,00,07,00,00,00,00,00,24,00,07,00,00,00,01,05,00,00,00,\ 00,00,05,15,00,00,00,6b,d6,62,04,07,e9,94,2d,15,25,af,47,f5,01,00,00,00,00,\ 18,00,07,00,00,00,01,02,00,00,00,00,00,05,20,00,00,00,22,02,00,00,00,00,14,\ 00,07,00,00,00,01,01,00,00,00,00,00,05,07,00,00,00,00,00,14,00,07,00,00,00,\ 01,01,00,00,00,00,00,01,00,00,00,00,00,00,14,00,07,00,00,00,01,01,00,00,00,\ 00,00,05,04,00,00,00,00,00,14,00,07,00,00,00,01,01,00,00,00,00,00,05,02,00,\ 00,00,00,00,14,00,07,00,00,00,01,01,00,00,00,00,00,05,12,00,00,00,3b,00,2e,\ 00,56,00,42,00,01,02,00,00,00,00,00,05,20,00,00,00,20,02,00,00,01,02,00,00,\ 00,00,00,05,20,00,00,00,20,02,00,00 "EnableDCOM"="Y" "LegacyAuthenticationLevel"=dword:00000002 "DefaultAccessPermission"=hex:01,00,04,80,d8,00,00,00,e8,00,00,00,00,00,00,00,\ 14,00,00,00,02,00,c4,00,08,00,00,00,00,00,24,00,07,00,00,00,01,05,00,00,00,\ 00,00,05,15,00,00,00,6b,d6,62,04,07,e9,94,2d,15,25,af,47,f5,01,00,00,00,00,\ 18,00,07,00,00,00,01,02,00,00,00,00,00,05,20,00,00,00,22,02,00,00,00,00,14,\ 00,07,00,00,00,01,01,00,00,00,00,00,05,0a,00,00,00,00,00,14,00,07,00,00,00,\ 01,01,00,00,00,00,00,05,07,00,00,00,00,00,14,00,07,00,00,00,01,01,00,00,00,\ 00,00,01,00,00,00,00,00,00,14,00,07,00,00,00,01,01,00,00,00,00,00,05,04,00,\ 00,00,00,00,14,00,07,00,00,00,01,01,00,00,00,00,00,05,02,00,00,00,00,00,14,\ 00,07,00,00,00,01,01,00,00,00,00,00,05,12,00,00,00,53,00,5c,00,73,00,79,00,\ 01,02,00,00,00,00,00,05,20,00,00,00,20,02,00,00,01,02,00,00,00,00,00,05,20,\ 00,00,00,20,02,00,00 [HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\Ole\AppCompat] [HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\Ole\AppCompat\ActivationSecurityCheckExemptionList] "{A50398B8-9075-4FBF-A7A1-456BF21937AD}"="1" "{AD65A69D-3831-40D7-9629-9B0B50A93843}"="1" "{0040D221-54A1-11D1-9DE0-006097042D69}"="1" "{2A6D72F1-6E7E-4702-B99C-E40D3DED33C3}"="1" [HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\Ole\NONREDIST] "System.EnterpriseServices.Thunk.dll"=""